Ketamine infusion therapy has recently been shown to have beneficial effects on clinically depressed patients.
The technique is still performed as an infusion but in a smaller dose and shorter duration than required for pain management. All details of ketamine infusion therapy as explained in this site that are not specific to the action in pain management apply equally to depression. I encourage any prospective depression patient to use the search engine of your choice to fully investigate ketamine infusion therapy before requesting treatment.
Recently performed and published studies have shown that a somewhat lower dose of ketamine infused over one hour have had dramatic positive effects on clinical depression, especially in cases refractory to standard treatment. The results indicate a rather immediate resolution of depression, however have yet to show any reasonably prolonged result, with many patients realizing one to two weeks of relief. An additional benefit may be found in results which seem to indicate a greatly accelerated clinical response to traditional anti-depressant medications, in many cases showing clinical response in as little as one week as opposed to four to twelve weeks. There may be a clear benefit in a coordinated therapy of a single one hour ketamine infusion combined with a newly prescribed oral anti-depressant pill with a result of immediate relief of depression from the ketamine infusion with continued and hopefully long term relief resulting from the accelerated effects of the oral pill.
In particularly severe cases of clinical depression ketamine infusion therapy can be used to allow standard treatment to benefit by diminishing the severity of depression.
In those cases which have failed all traditional forms of anti-depressant treatment, and as a result have no further option than Electro Convulsive Therapy (ECT), it may be reasonable to try a single ketamine infusion. When factoring all the negative side effects of ECT such as damage to additional areas of the brain or permanent change in affect, etc., into the equation, ketamine may be a better choice. In the doses used in treatment of depression, there is little chance of additional damage or change in affect except of course the loss of depression.
Even taking into consideration that the effect of ketamine may be short, weigh the advantages and disadvantages of ECT vs. weekly ketamine infusions, if necessary.
We are always trying to improve our techniques and are hoping to discover whether higher doses, consecutive infusions, or any other variance undertaken with complete patient safety may yield better and longer lasting results. Ketamine infusion therapy as a treatment of clinical depression is still relatively new, but safe. We are participating in a multi-disciplinary study to try and answer many of these questions.
We have actual clinical experience demonstrating resolution of depression with treatment by ketamine infusion therapy. Any patient wishing to receive treatment for depression using ketamine administered by Dr. Leverone should first fully investigate the drug, as well as the published reports of therapy, and must remember that like any ketamine infusion therapy treatment of depression utilizing ketamine infusion is purely elective and there is no guarantee whatsoever of any beneficial result.
If any patient wishes to proceed, please complete the contact form and also send an email to firstname.lastname@example.org